CJC-1295 + Ipamorelin
Research Use Only | Not for Human Consumption
A research blend of CJC-1295 and Ipamorelin, two synthetic growth-hormone-releasing peptides, supplied in lyophilized form.
A two-peptide research blend combining CJC-1295, a synthetic GHRH analog, and Ipamorelin, a synthetic pentapeptide ghrelin-receptor (GHS-R1a) agonist. Each component has been examined in preclinical and clinical publications for interactions with distinct receptors involved in growth-hormone secretion signaling.
Blend Components
| Component | CAS# | Formula | Molar Mass |
|---|---|---|---|
| CJC-1295 | 863288-34-0 | C₁₆₅H₂₇₁N₄₇O₄₆ | 3647.28 g/mol |
| Ipamorelin | 170851-70-4 | C₃₈H₄₉N₉O₅ | 711.85 g/mol |
All products are shipped in lyophilized form and must be reconstituted for in-vitro research applications. Refer to the Certificate of Analysis for purity and identity specifications.
A research blend of CJC-1295 and Ipamorelin, two synthetic growth-hormone-releasing peptides
What is CJC-1295 + Ipamorelin?
This blend brings together two peptides with different origin stories. CJC-1295 was developed by ConjuChem Biotechnologies, a Canadian biotech company, in the early 2000s as a long-acting synthetic analog of growth-hormone-releasing hormone (GHRH) for use in preclinical and clinical research.
Ipamorelin was characterized in the late 1990s by researchers at Novo Nordisk in Denmark as part of a program investigating selective growth-hormone secretagogues. Published research described it as a pentapeptide agonist at the GHS-R1a (ghrelin) receptor, noted in the literature for its selectivity relative to earlier GH-secretagogue compounds.
Subsequent preclinical and clinical publications have examined CJC-1295 for its effects on GH pulse amplitude via GHRH-receptor signaling, and Ipamorelin for its effects on pulse frequency via GHS-R1a signaling. Combination research has examined these dual-mechanism interactions at the level of the GH/IGF-1 axis in laboratory settings.
CJC-1295 and Ipamorelin continue to appear in peer-reviewed preclinical and clinical publications investigating growth-hormone-secretagogue pharmacology. This product is intended for research use only.
What is CJC-1295 + Ipamorelin studied for?
The following research areas represent documented studies available in the scientific literature. We make no claims regarding the benefits, efficacy, or therapeutic applications of this product.
GHRH Receptor Signaling Research
In clinical investigations, CJC-1295 has been examined for dose-dependent changes in circulating GH and IGF-1 biomarker levels following GHRH-receptor activation.
GH Pulsatility Research
Published clinical studies have examined CJC-1295's effects on pulsatile GH secretion parameters, including trough levels and pulse-frequency measurements.
Preclinical GH-Axis Research
Preclinical investigations in GHRH-deficient animal models have examined CJC-1295's effects on GH-axis endpoints and growth-related measurements.
GHS-R1a Selectivity & PK/PD Research
Ipamorelin has been characterized in published research for its selectivity at the GHS-R1a receptor and its pharmacokinetic/pharmacodynamic profile in clinical volunteers.
How should CJC-1295 + Ipamorelin be stored?
All of our products are manufactured using the Lyophilization (Freeze Drying) process, which ensures that our products remain 100% stable for shipping for up to 3-4 months.
Once the peptides are reconstituted (mixed with bacteriostatic water), they must be stored in the fridge to maintain stability.
After reconstitution, the peptides will remain stable for up to 30 days.
Certificate of Analysis
All CJC-1295 + Ipamorelin batches are independently tested by a third-party laboratory for purity and identity verification via HPLC with UV detection coupled with Mass Spectrometry.
HPLC Purity
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No Certificate of Analysis is available for the selected size yet. Contact support for batch-specific documentation.
COA documents are updated with each new batch. Contact support for batch-specific documentation.
Related Research Compounds
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Clinical References
- Ionescu M, Frohman LA. Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog. J Clin Endocrinol Metab. 2006;91(12):4792-4797. PubMed: 17018654
- Teichman SL, Neale A, Lawrence B, et al. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab. 2006;91(3):799-805. PubMed: 16352683
- Sinha DK, Balasubramanian A, Tatem AJ, et al. Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males. Transl Androl Urol. 2020;9(Suppl 2):S149-S159.
- Raun K, Hansen BS, Johansen NL, et al. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998;139(5):552-561. PubMed: 9849822
- Gobburu JV, Agersu00f8 H, Jusko WJ, Ynddal L. Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers. Pharm Res. 1999;16(9):1412-1416. PubMed: 10496658









