Thymosin Alpha-1
Research Use Only | Not for Human Consumption
A synthetic 28-amino-acid N-terminally acetylated peptide (Tα1) derived from prothymosin alpha, supplied in lyophilized form for laboratory research.
Chemistry
| CAS# | Formula | Molar Mass |
|---|---|---|
| CAS Number: 62304-98-7 | Molecular Formula: C129H215N33O55 | Molar Mass: 3108.30 g/mol |
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A 28-amino-acid thymic peptide studied for immune-signaling and T-cell research
Thymosin Alpha-1 (Tα1) is a synthetic 28-amino-acid, N-terminally acetylated peptide (Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN) derived from the precursor protein prothymosin alpha and widely used as a reference immunomodulatory peptide in laboratory research. It is supplied as a lyophilized powder strictly for research use only and is not for human consumption.
What is Thymosin Alpha-1?
Thymosin Alpha-1 (Tα1) was first isolated in the 1970s from thymosin fraction 5, a thymic tissue extract characterized by Allan Goldstein and colleagues. It was later identified as a 28-amino-acid, N-terminally acetylated fragment of the precursor protein prothymosin alpha, and is commonly described as a reference immunomodulatory thymic peptide.
As a research compound, Thymosin Alpha-1 has been the subject of an extensive preclinical and in vitro literature examining immune-signaling mechanisms — including T-cell maturation, Toll-like-receptor and dendritic-cell signaling, natural-killer-cell activity, and cytokine networks.
Peptide Foundry supplies Thymosin Alpha-1 as a high-purity lyophilized powder for laboratory investigators studying these immune-signaling pathways. This product is intended for research use only and is not for human consumption.
How should Thymosin Alpha-1 be stored?
All of our products are manufactured using the Lyophilization (Freeze Drying) process, which ensures that our products remain 100% stable for shipping for up to 3-4 months.
Prepared samples must be stored in the fridge to maintain stability, and remain stable for up to 30 days when properly refrigerated.
Certificate of Analysis
Every batch of Thymosin Alpha-1 is tested by ILS Laboratories, an ISO/IEC 17025–accredited lab, for purity, identity, heavy metals, sterility, endotoxin, and a fentanyl screen. The full certificate is below.
Thymosin Alpha-1 · 10mg
Peptide Purity · HPLC @ 214 nm
99.33% — exceptional research-grade purity
Area-normalized against all peptide-related peaks. Identity confirmed by chromatographic retention-time match to a reference standard.
Every test on this certificate
COA documents are updated with each new batch. Contact support for batch-specific documentation.
References
- Romani L, Bistoni F, Gaziano R, et al. Thymosin alpha 1 activates dendritic cells for antifungal Th1 resistance through toll-like receptor signaling. Blood. 2004;103(11):4232-9.
