PT-141
Research Use Only | Not for Human Consumption
A synthetic cyclic heptapeptide analog of alpha-MSH, supplied in lyophilized form.
Chemistry
| CAS# | Formula | Molar Mass |
|---|---|---|
| CAS Number: 189691-06-3 | Molecular Formula: C50H68N14O10 | Molar Mass: 1025.2 g/mol |
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A synthetic melanocortin receptor agonist peptide
PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide derived from alpha-melanocyte-stimulating hormone. In preclinical research, it has been examined as an agonist of melanocortin receptors, with a focus on MC4R binding and downstream intracellular signaling in neuronal cell models.
What is PT-141?
PT-141, also called Bremelanotide, originated from Melanotan 2 research at the University of Arizona. Scientists there were characterizing melanocortin receptor analogs and observed MC4R-mediated signaling activity distinct from the melanogenesis pathways that were the original focus of investigation.
Researchers subsequently modified the Melanotan 2 structure to produce a cyclic heptapeptide with altered receptor selectivity. The resulting compound, PT-141, has since appeared in peer-reviewed preclinical publications examining melanocortin receptor binding and central nervous system signaling.
In preclinical models, Bremelanotide has been examined for its melanocortin receptor pharmacology. The research-grade form is used in melanocortin receptor signaling studies. This product is intended for research use only and is not for human consumption.
How should PT-141 be stored?
All of our products are manufactured using the Lyophilization (Freeze Drying) process, which ensures that our products remain 100% stable for shipping for up to 3-4 months.
Prepared samples must be stored in the fridge to maintain stability, and remain stable for up to 30 days when properly refrigerated.
Certificate of Analysis
All PT-141 batches are independently tested by a third-party laboratory for purity and identity verification via HPLC with UV detection coupled with Mass Spectrometry.
HPLC Purity
99.872%
Product
PT-141 — 10mg
Lot Number
PT312
Appearance
White Lyophilized Powder
Test Method
HPLC-UV / Mass Spectrometry
Report Date
03/15/2026
COA Number
2603130191
Laboratory
Freedom Diagnostics
No Certificate of Analysis is available for the selected size yet. Contact support for batch-specific documentation.
COA documents are updated with each new batch. Contact support for batch-specific documentation.
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References
- Pfaus JG, et al. Selective facilitation of sexual solicitation in the female rat by a melanocortin receptor agonist. Proceedings of the National Academy of Sciences. 2004.
