TH9507
Research Use Only | Not for Human Consumption
A synthetic 44-amino-acid analog of human growth hormone-releasing hormone (GHRH) with a trans-3-hexenoic acid modification at Tyr1
Chemistry
| CAS# | Formula | Molar Mass |
|---|---|---|
| CAS Number: 218949-48-5 | Molecular Formula: C221H366N72O67S | Molar Mass: 5135.9 g/mol |
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A 44-amino-acid GHRH analog with a trans-3-hexenoic acid modification; CAS 218949-48-5
A synthetic GHRH analog stabilized by an N-terminal trans-3-hexenoic acid group that resists enzymatic degradation. Published preclinical research has examined its interactions with the pituitary GHRH receptor (GHRHR) and downstream somatotroph signaling pathways.
What is TH9507?
TH9507 was developed in the early 2000s by Theratechnologies, a Canadian pharmaceutical company based in Montreal. The research team worked on analogs of growth hormone-releasing hormone (GHRH), building on earlier structural work with the native 44-amino-acid peptide.
The molecule is distinguished by a trans-3-hexenoic acid group attached to the tyrosine at position 1. In preclinical characterization, this modification resists enzymatic breakdown while preserving receptor-binding activity of the parent GHRH sequence.
The compound has since appeared in published preclinical investigations of the GHRH receptor (GHRHR) and associated somatotroph signaling pathways. This product is intended for research use only.
How should TH9507 be stored?
All of our products are manufactured using the Lyophilization (Freeze Drying) process, which ensures that our products remain 100% stable for shipping for up to 3-4 months.
Prepared samples must be stored in the fridge to maintain stability, and remain stable for up to 30 days when properly refrigerated.
Certificate of Analysis
Every batch of TH9507 is tested by Freedom Diagnostics for purity, identity, heavy metals, sterility, and endotoxin. The full certificate is below.
TH9507 · 10mg
Peptide Purity · HPLC @ 214 nm
99.79% — exceptional research-grade purity
Area-normalized against all peptide-related peaks. Identity confirmed by chromatographic retention-time match to a reference standard.
Every test on this certificate
COA documents are updated with each new batch. Contact support for batch-specific documentation.
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References
- Falutz J, et al. New England Journal of Medicine. 2007. PubMed: 18057338
- Stanley TL, et al. JAMA. 2014. PubMed: 25038357
- Falutz J, et al. Journal of Clinical Endocrinology & Metabolism. 2007. PubMed: 20101189
- Makimura H, et al. Journal of Clinical Endocrinology & Metabolism. 2015.
