Ipamorelin
Research Use Only | Not for Human Consumption
A synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NHu2082)
Chemistry
| CAS# | Formula | Molar Mass |
|---|---|---|
| CAS Number: 170851-70-4 | Molecular Formula: C38H49N9O5 | Molar Mass: 711.9 g/mol |
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A synthetic pentapeptide GHS-R1a agonist
Ipamorelin is a synthetic pentapeptide and growth hormone secretagogue receptor (GHS-R1a) agonist. In preclinical investigations, it has been examined for interactions with the ghrelin-receptor pathway and for selectivity relative to ACTH, cortisol, and prolactin pathways.
What is Ipamorelin?
Ipamorelin was developed by scientists at Novo Nordisk in Denmark during the late 1990s. Researchers were investigating growth hormone secretagogues and sought a compound with a narrower receptor-interaction profile than earlier GHRPs such as GHRP-6, which had been associated with changes in cortisol levels and appetite-related signaling in preclinical work.
The Novo Nordisk team designed Ipamorelin as a pentapeptide targeting the ghrelin receptor (GHS-R1a). In their characterization work, published by Raun and colleagues in 1998, they reported GH release with minimal measured effects on ACTH, cortisol, or prolactin in the preclinical models examined.
Since that initial characterization, Ipamorelin has appeared in peer-reviewed preclinical publications examining GHS-R1a pharmacology, pharmacokinetic modeling, and skeletal endpoints in rodent models. This product is intended for research use only.
How should Ipamorelin be stored?
All of our products are manufactured using the Lyophilization (Freeze Drying) process, which ensures that our products remain 100% stable for shipping for up to 3-4 months.
Prepared samples must be stored in the fridge to maintain stability, and remain stable for up to 30 days when properly refrigerated.
Certificate of Analysis
All Ipamorelin batches are independently tested by a third-party laboratory for purity and identity verification via HPLC with UV detection coupled with Mass Spectrometry.
HPLC Purity
99.878%
Product
Ipamorelin — 10mg
Lot Number
IPA31226
Appearance
White Lyophilized Powder
Test Method
HPLC-UV / Mass Spectrometry
Report Date
03/15/2026
COA Number
2603130199
Laboratory
Freedom Diagnostics
No Certificate of Analysis is available for the selected size yet. Contact support for batch-specific documentation.
COA documents are updated with each new batch. Contact support for batch-specific documentation.
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References
- Raun K, et al. Ipamorelin, the first selective growth hormone secretagogue. European Journal of Endocrinology. 1998. PubMed: 9849822
- Gobburu JV, et al. Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide. Pharmaceutical Research. 1999. PubMed: 10496658
- Svensson J, et al. The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats. Journal of Endocrinology. 2000. PubMed: 10828840
