BPC-157 + TB-500
Research Use Only · Not for Human Consumption
A research blend of BPC-157 and TB-500 supplied in lyophilized form.
Combined peptides for tissue regeneration studies
Blend Components
| Component | CAS# | Formula | Molar Mass |
|---|---|---|---|
| CAS Number: BPC-157 | Molecular Formula: 137525-51-0 | Molar Mass: C62H98N16O22 | 1419.55 g/mol |
| TB-500 | 77591-33-4 | C212H350N56O78S | 4963.44 g/mol |
What is BPC-157 + TB-500?
A two-peptide research blend combining BPC-157 and TB-500. Each component has been examined in preclinical publications for interactions with distinct molecular pathways — BPC-157 for VEGFR2 and nitric-oxide signaling, and TB-500 for G-actin sequestration.
This blend combines two peptides that were discovered decades apart but ended up being natural partners in research. BPC-157 came from Croatian scientists in the early 1990s who were studying the protective properties of stomach fluid. TB-500, on the other hand, traces back to the 1960s when Dr. Allan Goldstein and his team at the National Institutes of Health were exploring the thymus gland and discovered a family of peptides called thymosins.
Researchers noticed that these two peptides seemed to tackle tissue repair from different angles. BPC-157 has been studied for its interactions with angiogenic signaling pathways in preclinical models. TB-500 has been researched for its role in actin regulation and cellular migration—mechanisms that are of interest in tissue repair research. Scientists started wondering: what if you used both at once?
Studies combining the two peptides have appeared in preclinical wound-model and musculoskeletal-model research. This product is intended for research use only.
How should BPC-157 + TB-500 be stored?
Peptide Foundry research peptides are supplied lyophilized (freeze-dried). Keep sealed vials cool, dry, and protected from light until reconstitution.
After reconstitution, refrigerate prepared solutions and use sterile technique. For general laboratory diluent and handling notes, see lyophilized peptide reconstitution.
Certificate of Analysis
Every batch of BPC-157 + TB-500 is tested by ILS Laboratories, an ISO/IEC 17025–accredited lab, for purity, identity, heavy metals, sterility, endotoxin, and a fentanyl screen. The full certificate is below.
BPC-157 / TB-500 · 10mg/10mg
Peptide Purity · HPLC @ 214 nm
99.60% — exceptional research-grade purity
Area-normalized against all peptide-related peaks. Identity confirmed by chromatographic retention-time match to a reference standard.
Every test on this certificate
COA documents are updated with each new batch. Contact support for batch-specific documentation.
Further reading
References
- Brcic L, Brcic I, Staresinic M, et al. Modulatory effect of gastric pentadecapeptide BPC 157 on angiogenesis in muscle and tendon healing. J Physiol Pharmacol. 2009;60 Suppl 7:191-196. PubMed: 20388964
- Staresinic M, Petrovic I, Novinscak T, et al. Effective therapy of transected quadriceps muscle in rat: Gastric pentadecapeptide BPC 157. J Orthop Res. 2006;24(5):1109-1117. PubMed: 16609979
- Goldstein AL, Hannappel E, Sosne G, Kleinman HK. Thymosin beta4: a multi-functional regenerative peptide. Basic properties and clinical applications. Expert Opin Biol Ther. 2012;12(1):37-51. PubMed: 22074294
- Bock-Marquette I, Saxena A, White MD, et al. Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair. Nature. 2004;432(7016):466-472. PubMed: 15565145
- Sikiric P, Seiwerth S, Rucman R, et al. Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract. Curr Pharm Des. 2011;17(16):1612-1632.
- Sosne G, Qiu P, Goldstein AL, Wheater M. Biological activities of thymosin beta4 defined by active sites in short peptide sequences. FASEB J. 2010;24(7):2144-2151.
