Glutathione
Research Use Only | Not for Human Consumption
A tripeptide composed of glutamate, cysteine, and glycine (γ-glutamyl-cysteinyl-glycine)
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Chemistry
| CAS# | Formula | Molar Mass |
|---|---|---|
| CAS Number: 70-18-8 | Molecular Formula: C10H17N3O6S | Molar Mass: 307.32 g/mol |
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A tripeptide of glutamate, cysteine, and glycine (γ-glutamyl-cysteinyl-glycine)
Glutathione (GSH) is a naturally occurring reduced tripeptide (γ-glutamyl-cysteinyl-glycine) present in most mammalian cells. It has been examined in preclinical research for its participation in intracellular thiol redox chemistry, glutathione S-transferase conjugation reactions, and GSH/GSSG-dependent signaling.
What is Glutathione?
Glutathione was first identified in 1888 by French researcher J. de Rey-Pailhade, who isolated the compound from yeast and called it 'philothion.' The name was later changed to glutathione in 1921 when Frederick Hopkins crystallized it and characterized its structure as a tripeptide containing a sulfhydryl group.
Research on glutathione expanded through the mid-20th century as biochemists characterized its distribution across mammalian cell types. Studies documented glutathione synthesis in nearly every cell type, with particularly high concentrations observed in hepatic tissue.
Glutathione has appeared in peer-reviewed publications spanning biochemistry, toxicology, immunology, and cell biology, where it is referenced in research on intracellular redox chemistry and thiol-dependent enzymatic pathways. This product is intended for research use only.
How should Glutathione be stored?
All of our products are manufactured using the Lyophilization (Freeze Drying) process, which ensures that our products remain 100% stable for shipping for up to 3-4 months.
Prepared samples must be stored in the fridge to maintain stability, and remain stable for up to 30 days when properly refrigerated.
Certificate of Analysis
All Glutathione batches are independently tested by a third-party laboratory for purity and identity verification via HPLC with UV detection coupled with Mass Spectrometry.
HPLC Purity
99.641%
Product
L-Glutathione — 1500mg
Lot Number
35264
Appearance
Lyophilized peptide vial
Test Method
RP-HPLC with UV detection
Report Date
03/18/2026
COA Number
35264
Laboratory
Chromate
No Certificate of Analysis is available for the selected size yet. Contact support for batch-specific documentation.
COA documents are updated with each new batch. Contact support for batch-specific documentation.
Identity & Handling
- Sequence
- γ-L-glutamyl-L-cysteinyl-glycine (Glu-Cys-Gly)
- Residues
- 3 — a tripeptide
- CAS Number
- 70-18-8
Also listed as
Glutathione · L-Glutathione · Reduced glutathione · GSH
Listing names differ between suppliers and change over time. The CAS number is the identifier that does not.
Measured purity
2 lots analysed to date, measuring 99.641% to 99.836% across 2 independent laboratories.
Published as measured, including the lowest result. Every lot ships with its own certificate; check the lot number on the vial against it rather than relying on a published range.
Further reading
References
- Forman HJ, et al. Glutathione: overview of its protective roles, measurement, and biosynthesis. Molecular Aspects of Medicine. 2009.
- Dröge W, Breitkreutz R. Glutathione and immune function. Proceedings of the Nutrition Society. 2000.
