Glutathione
Research Use Only · Not for Human Consumption
A tripeptide composed of glutamate, cysteine, and glycine (γ-glutamyl-cysteinyl-glycine)
A tripeptide of glutamate, cysteine, and glycine (γ-glutamyl-cysteinyl-glycine)
Chemistry
| CAS# | Formula | Molar Mass |
|---|---|---|
| CAS Number: 70-18-8 | Molecular Formula: C10H17N3O6S | Molar Mass: 307.32 g/mol |
What is Glutathione?
Glutathione (GSH) is a naturally occurring reduced tripeptide (γ-glutamyl-cysteinyl-glycine) present in most mammalian cells. It has been examined in preclinical research for its participation in intracellular thiol redox chemistry, glutathione S-transferase conjugation reactions, and GSH/GSSG-dependent signaling.
Glutathione was first identified in 1888 by French researcher J. de Rey-Pailhade, who isolated the compound from yeast and called it 'philothion.' The name was later changed to glutathione in 1921 when Frederick Hopkins crystallized it and characterized its structure as a tripeptide containing a sulfhydryl group.
Research on glutathione expanded through the mid-20th century as biochemists characterized its distribution across mammalian cell types. Studies documented glutathione synthesis in nearly every cell type, with particularly high concentrations observed in hepatic tissue.
Glutathione has appeared in peer-reviewed publications spanning biochemistry, toxicology, immunology, and cell biology, where it is referenced in research on intracellular redox chemistry and thiol-dependent enzymatic pathways. This product is intended for research use only.
How should Glutathione be stored?
Peptide Foundry research peptides are supplied lyophilized (freeze-dried). Keep sealed vials cool, dry, and protected from light until reconstitution.
After reconstitution, refrigerate prepared solutions and use sterile technique. For general laboratory diluent and handling notes, see lyophilized peptide reconstitution.
Certificate of Analysis
Every batch of Glutathione is tested by Freedom Diagnostics for purity, identity, heavy metals, sterility, and endotoxin. The full certificate is below.
Glutathione · 1500mg
Peptide Purity · HPLC @ 214 nm
99.08% — exceptional research-grade purity
Area-normalized against all peptide-related peaks. Identity confirmed by chromatographic retention-time match to a reference standard.
Every test on this certificate
COA documents are updated with each new batch. Contact support for batch-specific documentation.
Further reading
References
- Forman HJ, et al. Glutathione: overview of its protective roles, measurement, and biosynthesis. Molecular Aspects of Medicine. 2009.
- Dröge W, Breitkreutz R. Glutathione and immune function. Proceedings of the Nutrition Society. 2000.
