GLOW Blend
A triple-peptide blend (BPC-157 + TB-500 + GHK-Cu) studied in laboratory settings for tissue repair, collagen synthesis, and skin regeneration research
About GLOW Blend
GLOW is a research blend combining three peptides with documented preclinical activity profiles in tissue repair and regeneration: BPC-157's angiogenic signaling, TB-500's actin-regulatory cellular migration, and GHK-Cu's collagen synthesis and copper-mediated extracellular matrix remodeling.
GLOW combines three peptides that emerged from very different research traditions but converge on a shared biological domain: tissue repair and regeneration. BPC-157 came from Croatian gastric research in the early 1990s, TB-500 from National Institutes of Health thymus studies in the 1960s, and GHK-Cu from human serum aging research at UC San Francisco in 1973.
Each component peptide has been studied for distinct aspects of tissue regeneration in preclinical models. BPC-157 has been examined for VEGFR2-mediated angiogenic signaling and nitric oxide pathway modulation. TB-500 has been studied for actin sequestration and cellular migration toward injury sites. GHK-Cu has been investigated for collagen synthesis, lysyl oxidase activation, and gene expression changes in dermal fibroblasts.
Researchers studying skin regeneration, wound healing, and dermal biology have used GLOW as a tool for investigating how complementary tissue repair mechanisms interact. The blend brings together angiogenic signaling, cellular migration, and extracellular matrix remodeling in a single research-grade preparation.
Quick Facts
| BPC-157 CAS | 137525-51-0 |
|---|---|
| BPC-157 Formula | C₆₂H₉₈N₁₆O₂₂ |
| BPC-157 Molar Mass | 1419.55 g/mol |
| TB-500 CAS | 77591-33-4 |
| TB-500 Formula | C₂₁₂H₃₅₀N₅₆O₇₈S |
| TB-500 Molar Mass | 4963.44 g/mol |
| GHK-Cu CAS | 49557-75-7 |
| GHK-Cu Formula | C₁₄H₂₄N₆O₄·Cu |
| GHK-Cu Molar Mass | 402.92 g/mol |
| Form | Lyophilized powder |
| Purity | 99%+ (HPLC verified) |
| Third-Party Testing | Freedom Diagnostics (COA included) |
| Storage | Room temp 3–4 months; refrigerate post-reconstitution |
| Price (from) | $150.00 USD |
| SKU | PF-GLOW-BLEND |
How GLOW Blend Works
Preclinical studies have examined the three component peptides for distinct but complementary mechanisms in tissue repair: BPC-157 for vascular signaling, TB-500 for cellular migration, and GHK-Cu for collagen synthesis and matrix remodeling. Together, these mechanisms span multiple stages of tissue regeneration in research models.
Angiogenic Signaling (BPC-157)
BPC-157 has been studied in preclinical models for VEGFR2 receptor activation and downstream PI3K/Akt and MAPK signaling. Research has examined associated effects on endothelial cell proliferation, migration, and capillary tube formation in models of new blood vessel formation.
Cellular Migration (TB-500)
TB-500 has been studied for its role in sequestering G-actin monomers, modulating the actin cytoskeleton to enable cellular plasticity and motility. Preclinical research has examined enhanced migration of stem cells, endothelial cells, and keratinocytes toward sites of tissue damage.
Collagen Synthesis (GHK-Cu)
GHK-Cu has been examined in preclinical models for delivery of copper to lysyl oxidase, an enzyme that catalyzes collagen and elastin cross-linking. Research has documented increased collagen types I and III expression in fibroblast cultures treated with the copper-tripeptide complex.
Matrix Remodeling and Antioxidant Effects
GHK-Cu has additionally been studied for its modulation of matrix metalloproteinase activity and upregulation of antioxidant gene expression. These mechanisms complement the cellular migration and angiogenesis pathways activated by BPC-157 and TB-500 in preclinical regeneration research.
Frequently Asked Questions
- What is GLOW Blend?
- GLOW is a research blend combining three peptides with documented preclinical activity profiles in tissue repair and regeneration: BPC-157's angiogenic signaling, TB-500's actin-regulatory cellular migration, and GHK-Cu's collagen synthesis and copper-mediated extracellular matrix remodeling.
- What are the components of the GLOW Blend?
- The GLOW Blend contains BPC-157 (137525-51-0) and TB-500 (77591-33-4) and GHK-Cu (49557-75-7).
- What purity is Peptide Foundry's GLOW Blend?
- Peptide Foundry's research peptides are manufactured to 99%+ purity. Every batch is verified by an independent third-party laboratory (Freedom Diagnostics) using high-performance liquid chromatography (HPLC) for purity and identity, Limulus amebocyte lysate (LAL) assay for bacterial endotoxin, and inductively coupled plasma mass spectrometry (ICP-MS) for heavy-metal contamination. A Certificate of Analysis is published for every product and batch.
- How should GLOW Blend be stored?
- Lyophilized (freeze-dried) peptides are stable at room temperature for 3–4 months. Once reconstituted with bacteriostatic water, store refrigerated (2–8 °C) and use within 30 days. Keep away from direct light and extreme temperatures.
- Does GLOW Blend ship with a Certificate of Analysis?
- Yes. Every batch of every product ships with a Certificate of Analysis from Freedom Diagnostics, an independent third-party analytical laboratory. The COA documents HPLC purity, peptide identity, endotoxin testing, and heavy-metals screening.
- Is GLOW Blend sold for human use?
- No. All products sold by Peptide Foundry are strictly for in-vitro research and laboratory use only (RUO). They are not intended for human or animal consumption, therapeutic use, or diagnostic application.
Scientific References
- Sikiric P, et al. Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract. Curr Pharm Des. 2011;17(16):1612-1632. PubMed: 21548867
- Goldstein AL, et al. Thymosin beta4: a multi-functional regenerative peptide. Expert Opin Biol Ther. 2012;12(1):37-51. PubMed: 22074294
- Pickart L, Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci. 2018;19(7):1987. PubMed: 29986520
- Pickart L, Vasquez-Soltero JM, Margolina A. GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration. Biomed Res Int. 2015;2015:648108. PubMed: 26236730
This product is sold strictly for in-vitro research use only (RUO). It is not intended for human or animal consumption, therapeutic use, or diagnostic application.