What are the components of the BPC-157 / TB-500 Blend?

The BPC-157 / TB-500 Blend contains BPC-157 (137525-51-0) and TB-500 (77591-33-4).

What purity is Peptide Foundry's BPC-157 / TB-500 Blend?

Peptide Foundry's research peptides are manufactured to 99%+ purity. Every batch is verified by an independent third-party laboratory (Freedom Diagnostics) using high-performance liquid chromatography (HPLC) for purity and identity, Limulus amebocyte lysate (LAL) assay for bacterial endotoxin, and inductively coupled plasma mass spectrometry (ICP-MS) for heavy-metal contamination. A Certificate of Analysis is published for every product and batch.

How should BPC-157 / TB-500 Blend be stored?

Lyophilized (freeze-dried) peptides are stable at room temperature for 3–4 months. Once reconstituted with bacteriostatic water, store refrigerated (2–8 °C) and use within 30 days. Keep away from direct light and extreme temperatures.

Does BPC-157 / TB-500 Blend ship with a Certificate of Analysis?

Yes. Every batch of every product ships with a Certificate of Analysis from Freedom Diagnostics, an independent third-party analytical laboratory. The COA documents HPLC purity, peptide identity, endotoxin testing, and heavy-metals screening.

Is BPC-157 / TB-500 Blend sold for human use?

No. All products sold by Peptide Foundry are strictly for in-vitro research and laboratory use only (RUO). They are not intended for human or animal consumption, therapeutic use, or diagnostic application.

BPC-157 / TB-500 Blend

Name: BPC-157 / TB-500 Blend
Brand: Peptide Foundry
SKU: PF-BPC157TB500-10MG10MG
Price: 115.00 USD
Availability: InStock

A dual-peptide blend studied in laboratory settings for tissue repair and recovery mechanisms

About BPC-157 / TB-500 Blend

BPC-157 / TB-500 is a research blend combining BPC-157's studied angiogenic signaling with TB-500's actin-regulatory mechanisms. It has been designed for investigating complementary tissue repair pathways in preclinical models.

This blend combines two peptides that were discovered decades apart but ended up being natural partners in research. BPC-157 came from Croatian scientists in the early 1990s who were studying the protective properties of stomach fluid. TB-500, on the other hand, traces back to the 1960s when Dr. Allan Goldstein and his team at the National Institutes of Health were exploring the thymus gland and discovered a family of peptides called thymosins.

Researchers noticed that these two peptides seemed to tackle tissue repair from different angles. BPC-157 has been studied for its interactions with angiogenic signaling pathways in preclinical models. TB-500 has been researched for its role in actin regulation and cellular migration—mechanisms that are of interest in tissue repair research. Scientists started wondering: what if you used both at once?

That question led to studies combining the two peptides, and the results caught attention in the research community. Labs began using the blend to study wound healing, tissue recovery, and related biological processes. Today, BPC-157 + TB-500 is one of the most popular peptide combinations for tissue repair research.

Quick Facts

BPC-157 / TB-500 Blend Research Specifications
BPC-157 CAS	137525-51-0
BPC-157 Formula	C₆₂H₉₈N₁₆O₂₂
BPC-157 Molar Mass	1419.55 g/mol
TB-500 CAS	77591-33-4
TB-500 Formula	C₂₁₂H₃₅₀N₅₆O₇₈S
TB-500 Molar Mass	4963.44 g/mol
Form	Lyophilized powder
Purity	99%+ (HPLC verified)
Third-Party Testing	Freedom Diagnostics (COA included)
Storage	Room temp 3–4 months; refrigerate post-reconstitution
Price (from)	$115.00 USD
SKU	PF-BPC157TB500-10MG10MG

How BPC-157 / TB-500 Blend Works

In preclinical models, BPC-157 has been studied for its interactions with angiogenic signaling pathways, including VEGFR2 activation and nitric oxide modulation. TB-500 has been researched for its role in actin regulation and cellular migration. Together, this combination is investigated for complementary tissue repair mechanisms.

Angiogenic Signaling Research

BPC-157 has been studied for activation of VEGFR2 signaling and initiation of new blood vessel formation in preclinical models. TB-500 has been researched for its effects on endothelial cell differentiation and migration. Together, these dual mechanisms have been investigated for their roles in capillary network formation and vascular signaling.

Cell Migration & Proliferation

TB-500 has been studied for its effects on actin polymerization, enabling cell migration toward injury sites in preclinical models. BPC-157 has been researched for activation of FAK signaling and its effects on fibroblast, keratinocyte, and satellite cell migration in wound healing models.

Inflammatory Modulation Research

BPC-157 has been studied for modulation of prostaglandin pathways and NLRP3 inflammasome activity in preclinical models. TB-500 has been researched for effects on NF-κB signaling and pro-inflammatory cytokine production. Together, these mechanisms are investigated for anti-inflammatory signaling.

Collagen & Matrix Remodeling

Both peptides have been studied for effects on collagen synthesis (types I and III) and matrix metalloproteinase activity in preclinical models. This research examines how these mechanisms may influence tissue remodeling and extracellular matrix architecture.

Frequently Asked Questions

What is BPC-157 / TB-500 Blend?: BPC-157 / TB-500 is a research blend combining BPC-157's studied angiogenic signaling with TB-500's actin-regulatory mechanisms. It has been designed for investigating complementary tissue repair pathways in preclinical models.
What are the components of the BPC-157 / TB-500 Blend?: The BPC-157 / TB-500 Blend contains BPC-157 (137525-51-0) and TB-500 (77591-33-4).
What purity is Peptide Foundry's BPC-157 / TB-500 Blend?: Peptide Foundry's research peptides are manufactured to 99%+ purity. Every batch is verified by an independent third-party laboratory (Freedom Diagnostics) using high-performance liquid chromatography (HPLC) for purity and identity, Limulus amebocyte lysate (LAL) assay for bacterial endotoxin, and inductively coupled plasma mass spectrometry (ICP-MS) for heavy-metal contamination. A Certificate of Analysis is published for every product and batch.
How should BPC-157 / TB-500 Blend be stored?: Lyophilized (freeze-dried) peptides are stable at room temperature for 3–4 months. Once reconstituted with bacteriostatic water, store refrigerated (2–8 °C) and use within 30 days. Keep away from direct light and extreme temperatures.
Does BPC-157 / TB-500 Blend ship with a Certificate of Analysis?: Yes. Every batch of every product ships with a Certificate of Analysis from Freedom Diagnostics, an independent third-party analytical laboratory. The COA documents HPLC purity, peptide identity, endotoxin testing, and heavy-metals screening.
Is BPC-157 / TB-500 Blend sold for human use?: No. All products sold by Peptide Foundry are strictly for in-vitro research and laboratory use only (RUO). They are not intended for human or animal consumption, therapeutic use, or diagnostic application.

Scientific References

Brcic L, Brcic I, Staresinic M, et al. Modulatory effect of gastric pentadecapeptide BPC 157 on angiogenesis in muscle and tendon healing. J Physiol Pharmacol. 2009;60 Suppl 7:191-196. PubMed: 20388964
Staresinic M, Petrovic I, Novinscak T, et al. Effective therapy of transected quadriceps muscle in rat: Gastric pentadecapeptide BPC 157. J Orthop Res. 2006;24(5):1109-1117. PubMed: 16609979
Goldstein AL, Hannappel E, Sosne G, Kleinman HK. Thymosin beta4: a multi-functional regenerative peptide. Basic properties and clinical applications. Expert Opin Biol Ther. 2012;12(1):37-51. PubMed: 22074294
Bock-Marquette I, Saxena A, White MD, et al. Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair. Nature. 2004;432(7016):466-472. PubMed: 15565145

This product is sold strictly for in-vitro research use only (RUO). It is not intended for human or animal consumption, therapeutic use, or diagnostic application.